2022 Indianapolis Colts' schedule: Game-by-game predictions – Colts Wire

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The Indianapolis Colts released their official 2022 regular-season schedule Thursday, which means it’s time to predict the outcome of 17 games months into the future.
Doing these predictions need to be taken with massive amounts of salt—not just a grain—because we’re working with limited information when it comes to both the Colts and the teams they play in 2022.
With several new additions like quarterback Matt Ryan, defensive end Yannick Ngakoue and cornerback Stephon Gilmore, it will take time for these pieces to work together.
With all that said, here’s my way-too-early prediction for the Colts so feel free to roast me on social media (@KevinHickey11):
Carmen Mandato/Getty Images
Date: Sunday, Sept. 11
Time: 1:00 p.m. ET
Location: NRG Stadium
Broadcast: CBS
Prediction: Win, 28-17
The Colts have lost eight consecutive opening-season games. We’re well aware of that. But if there is a game to snap that streak, it’s this one. The Colts will be heavily favored and given that they stomped the Texans 31-0 at NRG Stadium just a season ago, the end result should be the same.
Record: 1-0
Julio Aguilar/Getty Images
Date: Sunday, Sept. 18
Time: 1:00 p.m. ET
Location: TIAA Bank Field
Broadcast: CBS
Prediction: Win, 23-20
They have to, right? There’s no way the Colts go all offseason talking about having a bad taste in their mouths just to lose this rematch. That taste will be well seasoned by the time this game rolls around and even though the Jaguars are stronger on paper, the Colts will be too hungry to make things right.
Record: 2-0
Jay Biggerstaff-USA TODAY Sports
Date: Sunday, Sept. 25
Time: 1:00 p.m. ET
Location: Lucas Oil Stadium
Broadcast: CBS
Prediction: Loss, 31-27
Home for the first time in 2022, the Colts get a tough matchup against one of the AFC’s best teams. This will be a good test to see where the Colts are in terms of competing with the top of the conference, but Patrick Mahomes and Travis Kelce prove to be too much.
Record: 2-1
Andy Lyons/Getty Images
Date: Sunday, Oct. 2
Time: 1:00 p.m. ET
Location: Lucas Oil Stadium
Broadcast: FOX
Prediction: Win, 24-21
After their first loss of the season, the Colts come back against a tough division foe that swept them in 2021. The loss of A.J. Brown will be too much as his replacement—Treylon Burks—still gets used to the NFL. Derrick Henry has a game, but the Colts are able to keep the Titans offense at bay.
Record: 3-1
Ron Chenoy-USA TODAY Sports
Date: Thursday, Oct. 6
Time: 8:15 p.m. ET
Location: Empower Field at Mile High
Broadcast: Prime Video
Prediction: Loss, 28-20
The game against the Titans is likely to be a physical one and turning around on a short week to fly to the mountains won’t do the Colts any favors. Russell Wilson will be a tough matchup regardless, and he’ll have a stable corps of receivers to work with against the Colts defense. In the end, it proves to be too much in their first prime-time game of the season.
Record: 3-2
AP Photo/Stephen B. Morton
Date: Sunday, Oct. 16
Time: 1:00 p.m. ET
Location: Lucas Oil Stadium
Broadcast: CBS
Prediction: Win, 21-18
The extra rest will help the Colts while Jonathan Taylor explodes for a three-touchdown game. It will be closer than expected, but the Colts finally pull off the season sweep over the Jaguars.
Record: 4-2
Andy Lyons/Getty Images
Date: Sunday, Oct. 23
Time: 1:00 p.m. ET
Location: Nissan Stadium
Broadcast: CBS
Prediction: Loss, 23-20
Derrick Henry goes bonkers on the Colts. They try to keep up with another strong game from Jonathan Taylor, but they wind up falling late in the fourth quarter on a go-ahead field goal by Tennessee.
Record: 4-3
John McCreary-USA TODAY Sports
Date: Sunday, Oct. 30
Time: 4:25 p.m. ET
Location: Lucas Oil Stadium
Broadcast: FOX
Prediction: Win, 19-16
The return of Carson Wentz comes at a perfect time as the Colts want to let off some steam. It’s an ugly game with several turnovers, but the Colts prevail against its former quarterback to get back into the win column,
Record: 5-3
Marc Lebryk-USA TODAY Sports
Date: Sunday, Nov. 6
Time: 1:00 p.m. ET
Location: Gillette Stadium
Broadcast: CBS
Prediction: Loss, 24-18
Jonathan Taylor was the hero for the Colts in the 2021 meeting, but there’s no magic this time. Bill Belichick finds a way to neutralize the run game enough to keep the Colts from mounting a game-winning drive.
Record: 5-4
pic
Date: Sunday, Nov. 13
Time: 4:05 p.m. ET
Location: Allegiant Stadium
Broadcast: CBS
Prediction: Loss, 31-28
Jonathan Taylor scores twice, and Matt Ryan finds both Michael Pittman Jr. and Alec Pierce for touchdowns. But the connection between Derek Carr and Davante Adams is enough to vault the Raiders to a win. The Colts lose back-to-back games for the first time.
Record: 5-5
Kim Klement-USA TODAY Sports
Date: Sunday, Nov. 20
Time: 1:00 p.m. ET
Location: Lucas Oil Stadium
Broadcast: CBS
Prediction: Win, 21-20
It’s a close game that features the rushing attack on both sides. The Colts find a way to pull it out by forcing Jalen Hurts to be uncomfortable in the pocket even though he adds a rushing score earlier in the game.
Record: 6-5
AP Photo/Justin Berl
Date: Monday, Nov. 28
Time: 8:15 p.m. ET
Location: Lucas Oil Stadium
Broadcast: ESPN
Prediction: Win, 28-21
Whether it will be Kenny Pickett or Mitchell Trubisky under center for the Steelers, the Colts take care of business at home. The question marks surrounding the quarterback position are enough to give the Colts the edge in this matchup.
Record: 7-5
pic
Date: Sunday, Dec. 4
Time: 8:20 p.m. ET
Location: AT&T Stadium
Broadcast: NBC
Prediction: Loss, 33-31
On Sunday Night Football, the Colts and Cowboys give the country a fireworks show. The Cowboys pull off the victory, but the Colts prove they can still hang with a high-powered offense in prime time. This game could go either way, but the Cowboys prevail at home.
Record: 7-6
AP Photo/Ross D. Franklin
The Colts go into the bye week ready to go on a late-season tear as they push for the top spot in the division.
Record: 7-6
Brace Hemmelgarn-USA TODAY Sports
Date: Saturday, Dec. 17 or Sunday, Dec. 18
Time: TBD
Location: U.S. Bank Stadium
Broadcast: TBD
Prediction: Win, 27-23
The Colts come out of the bye week fresh and take a road win over the Vikings. Even with the combination Justin Jefferson and Adam Theilen, the Colts are able to pressure Kirk Cousins enough to keep the Vikings offense at bay.
Record: 8-6
Jayne Kamin-Oncea-USA TODAY Sports
Date: Monday, Dec. 26
Time: 8:15 p.m. ET
Location: Lucas Oil Stadium
Broadcast: ESPN
Prediction: Loss, 30-26
Going against Justin Herbert in prime time won’t be an easy task. Maybe Gus Bradley’s experience against the young star will help, but Herbert is entering a new tier. It’s a close game, but Herbert pulls out the win in the end.
Record: 8-7
Joe Robbins/Getty Images
Date: Sunday, Jan. 1
Time: 1:00 p.m. ET
Location: MetLife Stadium
Broadcast: CBS
Prediction: Win, 28-17
The Giants are heading in the right direction, but they are also likely heading toward another top-10 pick. The Colts take care of business on the road with the AFC South crown in their sights.
Record: 9-7
Syndication: The Indianapolis Star
Date: Saturday, Jan. 7 or Sunday, Jan. 8
Time: TBD
Location: Lucas Oil Stadium
Broadcast: TBD
Prediction: Win, 31-14
With a chance to win the division, the Colts come out firing offensively. Jonathan Taylor scores two touchdowns while Michael Pittman Jr. and Mo Alie-Cox also add scores. The Colts finish at 10-7, which is enough to be crowned the AFC South champions for the first time since 2014.
Record: 10-7
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Here is the entire 2022 schedule for the Colts.
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